NHI.no
Annonse
Informasjon

Søvnapné hos voksne

Søvnapné gir symptomer som tretthet og slitenhet på dagtid. Bruk av CPAP (bildet) er en av flere mulige behandlinger av tilstanden.

Illustrasjonsfoto av en voksen mann som sover i sengen og bruker CPAP-maske.
Om tiltak som vektreduksjon og det å sove på siden ikke hjelper er CPAP-maske den beste behandlingen av søvnapné. Illustrasjonsfoto: Nicolesy/iStock

Sist oppdatert:

4. jan. 2024

Vil du vite mer

Dette dokumentet er basert på det profesjonelle dokumentet Søvnapné . Referanselisten for dette dokumentet vises nedenfor

  1. Greenstone M, Hack M. Obstructive sleep apnoea. BMJ. 2014;348:g3745.
  2. Semelka M, Wilson J, Floyd R. Diagnosis and treatment of obstructive sleep apnea in adults. Am Fam Physician 2016; 94: 355-60. American Family Physician
  3. Peppard PE, Young T, Barnet JH, et al. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 2013; 177: 1006. pmid:23589584 PubMed
  4. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med 2002; 165: 1217-39. PubMed
  5. Dematteis M, Pepin J-L, Jeanmart M, Deschaux C, Labarre-Vila A, Levy P. Charcot-Marie-Tooth disease and sleep apnoea syndrome: a family study. Lancet 2001; 357: 267-72. PubMed
  6. Jacobowitz O. Obstructive sleep apnoea in adults. BestPractice, last updated Jan 23, 2014 .
  7. Tveit RL, Lehmann S, Bjorvatn B. Prevalence of several somatic diseases depends on the presence and severity of obstructive sleep apnea. PLOS One 2018. doi:https://doi.org/10.1371/journal.pone.0192671
  8. Bjorvatn B, Rajakulendren N, Lehmann S, Pallesen S. Increased severity of obstructive sleep apnea is associated with less anxiety and depression. J Sleep Res. 2018 Dec;27(6):e12647. Epub 2017 Nov 29. PMID: 29193447. PubMed
  9. Povitz M, Bolo CE, Heitman SJ, Tsai WH, Wang J, James MT. Effect of treatment of obstructive sleep apnea on depressive symptoms: systematic review and meta-analysis. PLoS Med. 2014;11(11):e1001762.
  10. Qaseem A, et al. Diagnosis of obstructive sleep apnea in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2014;161(3):210–220.
  11. Peppard PE, Young T, Palta M, Dempsey J, Skatrud J. Longitudinal study of moderate weight change and sleep-disorder breathing. JAMA 2000; 284: 3015-21. PubMed
  12. Powell S, Kubba H, O'Brien C, Tremlett M. Pediatric obstructive sleep apnoea. Clinical review. BMJ 2010; 340: c1918. BMJ (DOI)
  13. Engstrøm M, Aarrestad S, Eldøen G, Alme A, Bjørge T, Miljeteig H, Bjorvatn B, Knudsen S, Indrekvam S, Nilsen KB. Nye anbefalinger for objektiv undersøkelse av søvn og søvnforstyrrelser. Tidsskr Nor Legeforen 2018; 138: 1805-6. doi:10.4045/tidsskr.18.0741 DOI
  14. Jennum PJ, Tønnesen P, Rasmussen N, Nørregaard O. Søvnrelaterede respirationsforstyrrelser. Diagnostik og behandling. Ugeskr Læger 2005; 167: 2385-9. PubMed
  15. Balachandran JS, Patel SR. In the clinic: obstructive sleep apnea. Ann Intern Med. 2014;161(9):ITC1–ITC15.
  16. Fenton ME, Heathcote K, Bryce R, et al. The utility of the elbow sign in the diagnosis of OSA. Chest. 2014;145(3):518–524.
  17. Arnardottir ES, Bjornsdottir E, Olafsdottir KA, et al. Obstructive sleep apnoea in the general population: highly prevalent but minimal symptoms. Eur Respir J. 2016 Jan;47(1):194-202. pmid:26541533 PubMed
  18. Ravichandran R, Gupta L, Singh M, Nag A, Thomas J, Panjiyar BK. The Interplay Between Sleep Disorders and Cardiovascular Diseases: A Systematic Review. Cureus. 2023 Sep 25;15(9):e45898. PMID: 37885512. PubMed
  19. Dudenbostel T, Calhoun DA. Resistant hypertension, obstructive sleep. Journal of Human Hypertension 2012; 26: 281-7. PubMed
  20. McEvoy RD, Antic NA, Heeley E, et al. CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea. N Engl J Med 2016 Aug 28. PMID: 27571048 PubMed
  21. Yu J, Zhou Z, McEvoy RD, et al. Association of Positive Airway Pressure With Cardiovascular Events and Death in Adults With Sleep Apnea: A Systematic Review and Meta-analysis. JAMA 2017; 318: 156.66. pmid:28697252 PubMed
  22. Randerath WJ, et al.; European Respiratory Society task force on non-CPAP therapies in sleep apnoea. Non-CPAP therapies in obstructive sleep apnoea. Eur Respir J. 2011;37(5):1000–1028.
  23. Foster GD, Borradaile KE, Sanders MH, et al. A randomized study on the effect of weight loss on obstructive sleep apnea among obese patients with type 2 diabetes. Arch Intern Med 2009; 169: 1619-26. PubMed
  24. Ronnebaum S, Bron M, Patel D, et al. Indirect treatment comparison of solriamfetol, modafinil, and armodafinil for excessive daytime sleepiness in obstructive sleep apnea. J Clin Sleep Med. 2021 Dec 1;17(12):2543-2555. PMID: 34402784. PubMed
  25. Mason M, Welsh EJ, Smith I. Drug therapy for obstructive sleep apnoea in adults. Cochrane Database Syst Rev. 2013 May 31;(5):CD003002. PMID: 23728641. PubMed
  26. Chapman JL, Kempler L, Chang CL, et al. Modafinil improves daytime sleepiness in patients with mild to moderate obstructive sleep apnoea not using standard treatments: a randomised placebo-controlled crossover trial. Thorax 2013. pmid:24287166 PubMed
  27. Mason M, Cates CJ, Smith I. Effects of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive sleep apnoea. Cochrane Database Syst Rev 2015; 7: CD011090. doi:10.1002/14651858.CD011090.pub2 DOI
  28. Weaver TE, Pepin JL, Schwab R, et al. Long-term effects of solriamfetol on quality of life and work productivity in participants with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea. J Clin Sleep Med. 2021 Oct 1;17(10):1995-2007. PMID: 34606437. PubMed
  29. Schweitzer PK, Mayer G, Rosenberg R, et al. Randomized Controlled Trial of Solriamfetol for Excessive Daytime Sleepiness in OSA: An Analysis of Subgroups Adherent or Nonadherent to OSA Treatment. Chest. 2021 Jul;160(1):307-318. Epub 2021 Feb 22. PMID: 33631141. PubMed
  30. Giles TL, Lasserson TJ, Smith B, et al. Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database of Syst Rev 2006, Issue 3. Art. No.: CD001106. DOI: 10.1002/14651858.CD001106.pub3. DOI
  31. Weaver TE, Mancini C, Maislin G, et al. Continuous positive airway pressure treatment of sleepy patients with milder obstructive sleep apnea: Results of the CPAP apnea trial north american program (CATNAP) randomized clinical trial. Am J Respir Crit Care Med 2012; 186: 677-83. PubMed
  32. Bratton DJ, Gaisl T, Wons AM, et al. CPAP vs Mandibular Advancement Devices and Blood Pressure in Patients With Obstructive Sleep Apnea: A Systematic Review and Meta-analysis. JAMA 2015; 314(21): 2280-93. pmid:PMID: 26624827 PubMed
  33. Marin JM, Agusti A, Villar I, et al. Association between treated and untreated obstructive sleep apnea and risk of hypertension. JAMA 2012; 307: 2169-76. Journal of the American Medical Association
  34. Gottlieb DJ, Punjabi NM, Mehra R, et al. CPAP versus oxygen in obstructive sleep apnea. N Engl J Med 2014 Jun 12;370(24):2276-85. PubMed
  35. Schwarz EI, Schlatzer C, Rossi VA, et al. Effect of CPAP Withdrawal on BP in OSA: Data from Three Randomized Controlled Trials. Chest. 2016; 150: 1202-10. PMID: 27452767 PubMed
  36. Marti S, Sampol G, Munoz X et al. Mortality in severe sleep apnoea/hypopnoea syndrome patients: impact of treatment. Eur Respir J 2002; 20: 1511-8. PubMed
  37. George CF. Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP. Thorax 2001; 56: 508-12. PubMed
  38. Povitz M, Bolo CE, Heitman SJ, et al. Effect of treatment of obstructive sleep apnea on depressive symptoms: systematic review and meta-analysis. PLoS Med. 2014; 11. doi: 10.1371/journal.pmed.1001762 DOI
  39. oGuzman MA, Sgambati FP, Pho H, et al. The Efficacy of Low-Level Continuous Positive Airway Pressure for the Treatment of Snoring. J Clin Sleep Med. 2017 May 15;13(5):703-711. PMID: 28356182. PubMed
  40. Lim J, Lasserson TJ, Fleetham J, Wright JJ. Oral appliances for obstructive sleep apnoea. Cochrane Database of Systematic Reviews 2006, Issue 1. Art. No.: CD004435. DOI: 10.1002/14651858.CD004435.pub3. DOI
  41. Sharples L, Glover M, Clutterbuck-James A, et al. Clinical effectiveness and cost-effectiveness results from the randomised controlled Trial of Oral Mandibular Advancement Devices for Obstructive sleep apnoea-hypopnoea (TOMADO) and long-term economic analysis of oral devices and continuous positive airway pressure. Health Technol Assess. 2014;18:1-296. PMID: 25359435 PubMed
  42. Marklund M, Carlberg B, Forsgren L, et al. Oral appliance therapy in patients with daytime sleepiness and snoring or mild to moderate sleep apnea: a randomized clinical trial. JAMA Intern Med. 2015 Jun 1.
  43. Kent D, Stanley J, Aurora RN, et al. Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2021 Dec 1;17(12):2499-2505. PMID: 34351848. PubMed
  44. Sundaram S, Lim J, Lasserson TJ. Surgery for obstructive sleep apnoea in adults. Cochrane Database of Systematic Reviews 2005, Issue 4. Art. No.: CD001004. DOI: 10.1002/14651858.CD001004.pub2. DOI
  45. Maresch KJ. Hypoglossal Nerve Stimulation: Effective Longterm Therapy for Obstructive Sleep Apnea. AANA J. 2018 Oct;86(5):412-416. PMID: 31584412. PubMed
  46. Nasjonal kompetansetjeneste for søvnsykdommer (SOVno): Søvnapné hos voksne. Nettsiden besøkt 15.10.21. helse-bergen.no
  47. Randerath W, Verbraecken J, de Raaff CAL, et al. European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea. Eur Respir Rev. 2021 Nov 30;30(162):210200. PMID: 34853097. PubMed
  48. Saba ES, Kim H, Huynh P, Jiang N. Orofacial Myofunctional Therapy for Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis. Laryngoscope. 2024 Jan;134(1):480-495. PMID: 37606313. PubMed
  49. den Herder C, Schmeck J, Appelboom DJK, de Vries N. Risks of general anaesthesia in people with obstructive sleep apnoea. BMJ 2004; 329: 955-9. PubMed
  50. Campos-Rodriguez F, Martinez-Garcai MA, de la Cruz-Moron I, et al. Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment. Ann Intern Med 2012; 156: 115-22. PubMed
  51. Abourjeili J, Salameh E, Noureddine M, Bou Khalil P, Eid AA. Obstructive sleep apnea: Beyond the dogma of obesity! Respir Med. 2023 Dec 28;222:107512. Epub ahead of print. PMID: 38158138. PubMed
  52. Tuomilehto HP, Seppä JM, Partinen MM, et al, for the Kuopio Sleep Apnea Group. Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea. Am J Respir Crit Care Med 2009; 179: 320-7. PubMed
  53. Bradley TD, Floras JS. Obstructive sleep apnoea and its cardiovascular consequences. Lancet 2009; 373: 82-93. PubMed
Annonse
Annonse